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TF-1 is listed in the Power Transformers range at ChipApex. The manufacturer field lists MATRIX TECHNOLOGY INC.. Its product description is 8KVA three-phase 480V to three-p. Review the specifications below when checking this part for your BOM.
TF-1 is a human erythroleukemia cell line derived from bone marrow tissue. The cells exhibit a lymphoblastoid morphology, appearing round or spread out when adherent, with a diameter of 15-20 μm. Growth characteristics are defined as semi-adherent and semi-suspension. The cell line requires specific cytokines for proliferation; it depends entirely on Interleukin-3 (IL-3) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF). It does not respond to IL-5. TF-1 cells are classified under Biosafety Level 1.
Verify the specific strain designation and passage number upon receipt. Confirm that the supplier provides documentation attesting to the absence of mycoplasma contamination. Ensure storage conditions align with cryopreservation standards for mammalian cell lines. Check for updated biosafety level classifications relevant to your facility's protocols before handling.
Select this cell line specifically for investigations requiring IL-3 or GM-CSF dependent erythroid differentiation. It is suitable for studying hematopoietic development and leukemia mechanisms. Do not use if independent growth without exogenous cytokines is required. Consider the semi-adherent nature when planning assay formats that require strict suspension or adherence.
TF-1 represents a widely utilized immortalized cell line in biomedical science. Originating from human red leukemia cells, it serves as a standard model for erythropoiesis. Its unique cytokine dependency distinguishes it from other leukemic lines, providing a controlled system for analyzing growth factor responses in hematological malignancies.
No direct substitute part numbers are documented. Alternative models may include other IL-3-dependent lines such as Ba/F3 engineered for erythroid markers, though biological differences exist.
No, TF-1 cells completely depend on IL-3 or GM-CSF for survival and proliferation.
They exhibit a semi-adherent and semi-suspension growth pattern.
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